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Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery

Our previous study first investigated feasibility of applying ultrasound (US) and microbubbles (MBs) via external auditory canal to facilitate drug delivery into inner ear. However, most drugs are in aqueous formulae and eliminated via Eustachian tubes after drug application. In this study, feasibil...

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Détails bibliographiques
Publié dans:Drug Deliv
Auteurs principaux: Liao, Ai-Ho, Shih, Cheng-Ping, Li, Ming-Wei, Lin, Yi-Chun, Chuang, Ho-Chiao, Wang, Chih-Hung
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216251/
https://ncbi.nlm.nih.gov/pubmed/34142922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2021.1938758
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