Thermosensitive Polymer Blend Composed of Poloxamer 407, Poloxamer 188 and Polycarbophil for the Use as Mucoadhesive In Situ Gel

Herein, thermosensitive blends of poloxamer 407 (P407)/poloxamer 188 (P188)/polycarbophil (PCB) were developed in terms of maximized content of PCB (a mucoadhesive polymer) and desired temperature-dependent rheological properties of the blends as in situ gelling matrices. Maximizing PCB content whil...

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Hlavní autoři: Namon Hirun, Pakorn Kraisit, Vimon Tantishaiyakul
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-04-01
Edice:Polymers
Témata:
poloxamer 407
poloxamer 188
polycarbophil
thermosensitive hydrogels
mucoadhesive polymers
Box–Behnken design
On-line přístup:https://www.mdpi.com/2073-4360/14/9/1836
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