Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes

INSULIN-DEPENDENT diabetes mellitus (IDDM) in non-obese diabetic (NOD) mice results from the T-lymphocyte-mediated destruction of the insulin-producing pancreatic β-cells and serves as a model for human IDDM(1). Whereas a number of autoantibodies are associated with IDDM(2), it is unclear when and t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nature
Main Authors: Kaufman, Daniel L., Clare-Salzler, Michael, Tian, Jide, Forsthuber, Thomas, Ting, Grace S. P., Robinson, Paul, Atkinson, Mark A., Sercarz, Eli E., Tobin, Allan J., Lehmann, Paul V.
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216222/
https://ncbi.nlm.nih.gov/pubmed/7694152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/366069a0
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados