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Two Forms of the γ-Aminobutyric Acid Synthetic Enzyme Glutamate Decarboxylase Have Distinct Intraneuronal Distributions and Cofactor Interactions

Glutamate decarboxylase (GAD) catalyzes the production of γ-aminobutyric acid (GABA), a major inhibitory neurotransmitter. The mammalian brain contains two forms of GAD, with M(r)s of 67,000 and 65,000 (GAD(67) and GAD(65)). Using a new antiserum specific for GAD(67) and a monoclonal antibody specif...

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Bibliografski detalji
Izdano u:J Neurochem
Glavni autori: Kaufman, Daniel L., Houser, Carolyn R., Tobin, Allan J.
Format: Artigo
Jezik:Inglês
Izdano: 1991
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8194030/
https://ncbi.nlm.nih.gov/pubmed/1988566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.1991.tb08211.x
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