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Two Forms of the γ-Aminobutyric Acid Synthetic Enzyme Glutamate Decarboxylase Have Distinct Intraneuronal Distributions and Cofactor Interactions
Glutamate decarboxylase (GAD) catalyzes the production of γ-aminobutyric acid (GABA), a major inhibitory neurotransmitter. The mammalian brain contains two forms of GAD, with M(r)s of 67,000 and 65,000 (GAD(67) and GAD(65)). Using a new antiserum specific for GAD(67) and a monoclonal antibody specif...
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| Veröffentlicht in: | J Neurochem |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1991
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8194030/ https://ncbi.nlm.nih.gov/pubmed/1988566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.1991.tb08211.x |
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