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Clinical Implications of Colorectal Cancer Stem Cells in the Age of Single-Cell Omics and Targeted Therapies

The cancer stem cell (CSC) concept emerged from the recognition of inherent tumor heterogeneity and suggests that within a given tumor, in analogy to normal tissues, there exists a cellular hierarchy composed of a minority of more primitive cells with enhanced longevity (ie, CSCs) that give rise to...

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Pubblicato in:Gastroenterology
Autori principali: Frank, Markus H., Wilson, Brian J., Gold, Jason S., Frank, Natasha Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215897/
https://ncbi.nlm.nih.gov/pubmed/33617889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2020.12.080
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