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Expression of cytochrome P450 isozyme transcripts and activities in human livers

1. Individual differences in cytochrome P450 (CYP) enzymes contribute to responses to drugs and environmental chemicals. The expression of CYPs are influenced by sex, age and ethnicity. Human CYP studies are often conducted with human liver microsomes and liver cells to evaluate chemical induction a...

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Détails bibliographiques
Publié dans:Xenobiotica
Auteurs principaux: Liu, Jie, Lu, Yuan-Fu, Corton, J. Christopher, Klaassen, Curtis D.
Format: Artigo
Langue:Inglês
Publié: 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215780/
https://ncbi.nlm.nih.gov/pubmed/33350342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2020.1867929
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