Identifying Key Somatic Copy Number Alterations Driving Dysregulation of Cancer Hallmarks in Lower-Grade Glioma

Somatic copy-number alterations (SCNAs) are major contributors to cancer development that are pervasive and highly heterogeneous in human cancers. However, the driver roles of SCNAs in cancer are insufficiently characterized. We combined network propagation and linear regression models to design an...

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Vydáno v:Front Genet
Hlavní autoři: Zhou, Yao, Wang, Shuai, Yan, Haoteng, Pang, Bo, Zhang, Xinxin, Pang, Lin, Wang, Yihan, Xu, Jinyuan, Hu, Jing, Lan, Yujia, Ping, Yanyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Genetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215700/
https://ncbi.nlm.nih.gov/pubmed/34163522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.654736
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