Genomic copy number variation correlates with survival outcomes in WHO grade IV glioma

Allele-specific copy number analysis of tumors (ASCAT) assesses copy number variations (CNV) while accounting for aberrant cell fraction and tumor ploidy. We evaluated if ASCAT-assessed CNV are associated with survival outcomes in 56 patients with WHO grade IV gliomas. Tumor data analyzed by Affymet...

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Pubblicato in:Sci Rep
Autori principali: Buchwald, Zachary S., Tian, Sibo, Rossi, Michael, Smith, Geoffrey H., Switchenko, Jeffrey, Hauenstein, Jennifer E., Moreno, Carlos S., Press, Robert H., Prabhu, Roshan S., Zhong, Jim, Saxe, Debra F., Neill, Stewart G., Olson, Jeffrey J., Crocker, Ian R., Curran, Walter J., Shu, Hui-Kuo G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192941/
https://ncbi.nlm.nih.gov/pubmed/32355162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63789-9
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