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Integrating Transcriptome-Wide Association Study and mRNA Expression Profiling Identifies Novel Genes Associated With Osteonecrosis of the Femoral Head

OBJECTIVE: This study aims to identify novel candidate genes associated with osteonecrosis of the femoral head (ONFH). METHODS: A transcriptome-wide association study (TWAS) was performed by integrating the genome-wide association study dataset of osteonecrosis (ON) in the UK Biobank with pre-comput...

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הוצא לאור ב:	Front Genet
Main Authors:	Ma, Mei, Li, Peilin, Liu, Li, Cheng, Shiqiang, Cheng, Bolun, Liang, Chu Jun, Tan, Sijia, Li, Wenyu, Wen, Yan, Guo, Xiong, Wu, Cuiyan
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Frontiers Media S.A. 2021
נושאים:	Genetics
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC8215574/ https://ncbi.nlm.nih.gov/pubmed/34163523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.663080
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Integrating Transcriptome-Wide Association Study and mRNA Expression Profiling Identifies Novel Genes Associated With Osteonecrosis of the Femoral Head

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