Integrating Transcriptome-Wide Association Study and mRNA Expression Profiling Identifies Novel Genes Associated With Osteonecrosis of the Femoral Head

OBJECTIVE: This study aims to identify novel candidate genes associated with osteonecrosis of the femoral head (ONFH). METHODS: A transcriptome-wide association study (TWAS) was performed by integrating the genome-wide association study dataset of osteonecrosis (ON) in the UK Biobank with pre-comput...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Ma, Mei, Li, Peilin, Liu, Li, Cheng, Shiqiang, Cheng, Bolun, Liang, Chu Jun, Tan, Sijia, Li, Wenyu, Wen, Yan, Guo, Xiong, Wu, Cuiyan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215574/
https://ncbi.nlm.nih.gov/pubmed/34163523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.663080
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