Cyclophosphamide Exposure Causes Long-Term Detrimental Effect of Oocytes Developmental Competence Through Affecting the Epigenetic Modification and Maternal Factors’ Transcription During Oocyte Growth

Cyclophosphamide (CTX) is widely used in various cancer therapies and in immunosuppression, and patients can still have babies after CTX chemotherapy. CTX directly causes primordial follicle loss with overactivation and DNA damage-induced apoptosis. Previous studies have shown that maternal exposure...

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Detaylı Bibliyografya
Yayımlandı:Front Cell Dev Biol
Asıl Yazarlar: Yang, Weijie, Ma, Yerong, Jin, Jiamin, Ren, Peipei, Zhou, Hanjing, Xu, Shiqian, Zhang, Yingyi, Hu, Zhanhong, Rong, Yan, Dai, Yongdong, Zhang, Yinli, Zhang, Songying
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Cell and Developmental Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215553/
https://ncbi.nlm.nih.gov/pubmed/34164401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.682060
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