p65BTK Is a Novel Biomarker and Therapeutic Target in Solid Tumors

Bruton’s tyrosine kinase (BTK) is a non-receptor intracellular kinase playing a key role in the proliferation and survival of normal and malignant B-lymphocytes. Its targeting by Ibrutinib, the first specific inhibitor, represented a turning point for the therapy of certain types of B-cell leukemias...

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Bibliographic Details
Published in:Front Cell Dev Biol
Main Authors: Grassilli, Emanuela, Cerrito, Maria Grazia, Bonomo, Sara, Giovannoni, Roberto, Conconi, Donatella, Lavitrano, Marialuisa
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215537/
https://ncbi.nlm.nih.gov/pubmed/34164404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.690365
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