CLEC-2 Prevents Accumulation and Retention of Inflammatory Macrophages During Murine Peritonitis

Platelets play a key role in the development, progression and resolution of the inflammatory response during sterile inflammation and infection, although the mechanism is not well understood. Here we show that platelet CLEC-2 reduces tissue inflammation by regulating inflammatory macrophage activati...

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Bibliografiske detaljer
Udgivet i:Front Immunol
Main Authors: Bourne, Joshua H., Beristain-Covarrubias, Nonantzin, Zuidscherwoude, Malou, Campos, Joana, Di, Ying, Garlick, Evelyn, Colicchia, Martina, Terry, Lauren V., Thomas, Steven G., Brill, Alexander, Bayry, Jagadeesh, Watson, Steve P., Rayes, Julie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215360/
https://ncbi.nlm.nih.gov/pubmed/34163489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.693974
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