Comparison of genome-wide gene expression profiling by RNA Sequencing versus microarray in bronchial biopsies of COPD patients before and after inhaled corticosteroid treatment: does it provide new insights?

More DEGs are detected by RNA-Seq than microarrays in COPD lung biopsies and are associated with immunological pathways. Performing bulk tissue cell-type deconvolution in microarray lung samples, using the SVR method, reflects RNA-Seq results. https://bit.ly/2N8sY3s

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Bibliografiske detaljer
Udgivet i:ERJ Open Res
Main Authors: Ditz, Benedikt, Boekhoudt, Jeunard G., Aliee, Hananeh, Theis, Fabian J., Nawijn, Martijn, Brandsma, Corry-Anke, Hiemstra, Pieter S., Timens, Wim, Tew, Gaik W., Grimbaldeston, Michele A., Neighbors, Margaret, Guryev, Victor, van den Berge, Maarten, Faiz, Alen
Format: Artigo
Sprog:Inglês
Udgivet: European Respiratory Society 2021
Fag:
Original Research Letters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215328/
https://ncbi.nlm.nih.gov/pubmed/34164552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/23120541.00104-2021
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