STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer

BACKGROUND: Peritoneal carcinomatosis is a fatal clinical presentation of colon cancer, characterized by unresponsiveness to conventional anticancer therapies, including immune checkpoint inhibitors. Here, we elucidated the immune-evasion mechanisms during the peritoneal carcinomatosis of colon canc...

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Detalles Bibliográficos
Publicado en:J Immunother Cancer
Autores principales: Lee, Seung Joon, Yang, Hannah, Kim, Woo Ram, Lee, Yu Seong, Lee, Won Suk, Kong, So Jung, Lee, Hye Jin, Kim, Jeong Hun, Cheon, Jaekyung, Kang, Beodeul, Chon, Hong Jae, Kim, Chan
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215239/
https://ncbi.nlm.nih.gov/pubmed/34145029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002195
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