STING activation normalizes the intraperitoneal vascular-immune microenvironment and suppresses peritoneal carcinomatosis of colon cancer

BACKGROUND: Peritoneal carcinomatosis is a fatal clinical presentation of colon cancer, characterized by unresponsiveness to conventional anticancer therapies, including immune checkpoint inhibitors. Here, we elucidated the immune-evasion mechanisms during the peritoneal carcinomatosis of colon canc...

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Vydáno v:J Immunother Cancer
Hlavní autoři: Lee, Seung Joon, Yang, Hannah, Kim, Woo Ram, Lee, Yu Seong, Lee, Won Suk, Kong, So Jung, Lee, Hye Jin, Kim, Jeong Hun, Cheon, Jaekyung, Kang, Beodeul, Chon, Hong Jae, Kim, Chan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2021
Témata:
Oncolytic and Local Immunotherapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215239/
https://ncbi.nlm.nih.gov/pubmed/34145029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-002195
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