Next-Generation Sequencing Identifies Extended HLA Class I and II Haplotypes Associated With Early-Onset and Late-Onset Myasthenia Gravis in Italian, Norwegian, and Swedish Populations

Genetic susceptibility to myasthenia gravis (MG) associates with specific HLA alleles and haplotypes at the class I and II regions in various populations. Previous studies have only examined alleles at a limited number of HLA loci that defined only broad serotypes or alleles defined at the protein s...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Creary, Lisa E., Gangavarapu, Sridevi, Caillier, Stacy J., Cavalcante, Paola, Frangiamore, Rita, Lie, Benedicte A., Bengtsson, Mats, Harbo, Hanne Flinstad, Brauner, Susanna, Hollenbach, Jill A., Oksenberg, Jorge R., Bernasconi, Pia, Maniaol, Angelina Hatlø, Hammarström, Lennart, Mantegazza, Renato, Fernández-Viña, Marcelo A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215161/
https://ncbi.nlm.nih.gov/pubmed/34163474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.667336
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