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Asymmetric dynamics of dimeric SARS-CoV-2 and SARS-CoV main proteases in an apo form: Molecular dynamics study on fluctuations of active site, catalytic dyad, and hydration water

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been widely spread around the world. It is necessary to examine the viral proteins that play a notorious role in the invasion of our body. The main protease (3CL(pro)) facilitates the maturation of the coronavirus. It is thought that t...

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Detalhes bibliográficos
Publicado no:BBA Adv
Main Authors: Iida, Shinji, Fukunishi, Yoshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214910/
https://ncbi.nlm.nih.gov/pubmed/34235495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadva.2021.100016
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