Glucocorticoid receptor signaling in ventral tegmental area neurons increases the rewarding value of a high-fat diet in mice

The reward system, which consists of dopaminergic neurons projecting from the ventral tegmental area (VTA) to the nucleus accumbens and caudate-putamen in the striatum, has an important role in the pathogenesis of not only drug addiction but also diet-induced obesity. In the present study, we examin...

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Udgivet i:Sci Rep
Main Authors: Mizoguchi, Akira, Banno, Ryoichi, Sun, Runan, Yaginuma, Hiroshi, Taki, Keigo, Kobayashi, Tomoko, Sugiyama, Mariko, Tsunekawa, Taku, Onoue, Takeshi, Takagi, Hiroshi, Hagiwara, Daisuke, Ito, Yoshihiro, Iwama, Shintaro, Suga, Hidetaka, Nagai, Taku, Yamada, Kiyofumi, Arima, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213822/
https://ncbi.nlm.nih.gov/pubmed/34145364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92386-7
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