Hakai is required for stabilization of core components of the m(6)A mRNA methylation machinery

N(6)-methyladenosine (m(6)A) is the most abundant internal modification on mRNA which influences most steps of mRNA metabolism and is involved in several biological functions. The E3 ubiquitin ligase Hakai was previously found in complex with components of the m(6)A methylation machinery in plants a...

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Publié dans:Nat Commun
Auteurs principaux: Bawankar, Praveen, Lence, Tina, Paolantoni, Chiara, Haussmann, Irmgard U., Kazlauskiene, Migle, Jacob, Dominik, Heidelberger, Jan B., Richter, Florian M., Nallasivan, Mohanakarthik P., Morin, Violeta, Kreim, Nastasja, Beli, Petra, Helm, Mark, Jinek, Martin, Soller, Matthias, Roignant, Jean-Yves
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213727/
https://ncbi.nlm.nih.gov/pubmed/34145251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23892-5
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