Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy

T cell dysfunction occurs early following HIV infection, impacting the emergence of non-AIDS morbidities and limiting curative efforts. ART initiated during primary HIV infection (PHI) can reverse this dysfunction, but the extent of recovery is unknown. We studied 66 HIV-infected individuals treated...

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Vydáno v:Front Immunol
Hlavní autoři: Martin, Genevieve E., Sen, Debattama R., Pace, Matthew, Robinson, Nicola, Meyerowitz, Jodi, Adland, Emily, Thornhill, John P., Jones, Mathew, Ogbe, Ane, Parolini, Lucia, Olejniczak, Natalia, Zacharopoulou, Panagiota, Brown, Helen, Willberg, Christian B., Nwokolo, Nneka, Fox, Julie, Fidler, Sarah, Haining, W. Nicholas, Frater, John
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2021
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213372/
https://ncbi.nlm.nih.gov/pubmed/34149690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.647688
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