Epigenetic Features of HIV-Induced T-Cell Exhaustion Persist Despite Early Antiretroviral Therapy

T cell dysfunction occurs early following HIV infection, impacting the emergence of non-AIDS morbidities and limiting curative efforts. ART initiated during primary HIV infection (PHI) can reverse this dysfunction, but the extent of recovery is unknown. We studied 66 HIV-infected individuals treated...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Martin, Genevieve E., Sen, Debattama R., Pace, Matthew, Robinson, Nicola, Meyerowitz, Jodi, Adland, Emily, Thornhill, John P., Jones, Mathew, Ogbe, Ane, Parolini, Lucia, Olejniczak, Natalia, Zacharopoulou, Panagiota, Brown, Helen, Willberg, Christian B., Nwokolo, Nneka, Fox, Julie, Fidler, Sarah, Haining, W. Nicholas, Frater, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213372/
https://ncbi.nlm.nih.gov/pubmed/34149690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.647688
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