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Replacement of Arg in the conserved N-terminal RLFDQxFG motif affects physico-chemical properties and chaperone-like activity of human small heat shock protein HspB8 (Hsp22)

The small heat shock protein (sHsp) called HspB8 (formerly, Hsp22) is one of the least typical sHsp members, whose oligomerization status remains debatable. Here we analyze the effect of mutations in a highly conservative sequence located in the N-terminal domain of human HspB8 on its physico-chemic...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Shatov, Vladislav M., Sluchanko, Nikolai N., Gusev, Nikolai B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213154/
https://ncbi.nlm.nih.gov/pubmed/34143841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0253432
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