Llwytho...

Mutations in HspB1 and hereditary neuropathies

Charcot-Marie-Tooth (CMT) disease is major hereditary neuropathy. CMT has been linked to mutations in a range of proteins, including the small heat shock protein HspB1. Here we review the properties of several HspB1 mutants associated with CMT. In vitro, mutations in the N-terminal domain lead to a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Stress Chaperones
Prif Awduron: Muranova, Lydia K., Sudnitsyna, Maria V., Strelkov, Sergei V., Gusev, Nikolai B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Netherlands 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7332652/
https://ncbi.nlm.nih.gov/pubmed/32301006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-020-01099-9
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!