In silico comparative analysis of LRRK2 interactomes from brain, kidney and lung

Mutations in LRRK2 are the most frequent cause of familial Parkinson’s disease (PD), with common LRRK2 non-coding variants also acting as risk factors for idiopathic PD. Currently, therapeutic agents targeting LRRK2 are undergoing advanced clinical trials in humans, however, it is important to under...

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Vydáno v:Brain Res
Hlavní autoři: Verma, Amrita, Ebanks, Kirsten, Fok, Chi-Yee, Lewis, Patrick A., Bettencourt, Conceicao, Bandopadhyay, Rina
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier/North-Holland Biomedical Press 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212912/
https://ncbi.nlm.nih.gov/pubmed/33915162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2021.147503
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