IV and oral fosfomycin pharmacokinetics in neonates with suspected clinical sepsis

BACKGROUND: Fosfomycin has the potential to be re-purposed as part of a combination therapy to treat neonatal sepsis where resistance to current standard of care (SOC) is common. Limited data exist on neonatal fosfomycin pharmacokinetics and estimates of bioavailability and CSF/plasma ratio in this...

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Détails bibliographiques
Publié dans:J Antimicrob Chemother
Auteurs principaux: Kane, Zoe, Gastine, Silke, Obiero, Christina, Williams, Phoebe, Murunga, Sheila, Thitiri, Johnstone, Ellis, Sally, Correia, Erika, Nyaoke, Borna, Kipper, Karin, van den Anker, John, Sharland, Mike, Berkley, James A, Standing, Joseph F
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2021
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212774/
https://ncbi.nlm.nih.gov/pubmed/33855449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkab083
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