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Development of a Novel Multipenicillin Assay and Assessment of the Impact of Analyte Degradation: Lessons for Scavenged Sampling in Antimicrobial Pharmacokinetic Study Design

Penicillins are widely used to treat infections in children; however, the evidence is continuing to evolve in defining the optimal dosing. Modern pediatric pharmacokinetic study protocols frequently favor opportunistic, “scavenged” sampling. This study aimed to develop a small-volume single assay fo...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Kipper, Karin, Barker, Charlotte I. S., Standing, Joseph F., Sharland, Mike, Johnston, Atholl
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740359/
https://ncbi.nlm.nih.gov/pubmed/29084754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01540-17
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