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Haem is crucial for medium-dependent metronidazole resistance in clinical isolates of Clostridioides difficile

BACKGROUND: Until recently, metronidazole was the first-line treatment for Clostridioides difficile infection and it is still commonly used. Though resistance has been reported due to the plasmid pCD-METRO, this does not explain all cases. OBJECTIVES: To identify factors that contribute to plasmid-i...

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Bibliografische gegevens
Gepubliceerd in:J Antimicrob Chemother
Hoofdauteurs: Boekhoud, Ilse M, Sidorov, Igor, Nooij, Sam, Harmanus, Céline, Bos-Sanders, Ingrid M J G, Viprey, Virginie, Spittal, William, Clark, Emma, Davies, Kerrie, Freeman, Jane, Kuijper, Ed J, Smits, Wiep Klaas
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212768/
https://ncbi.nlm.nih.gov/pubmed/33876817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkab097
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