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Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis
ABSTRACT: All‐trans‐retinoic acid (atRA), the active metabolite of vitamin A, has antifibrogenic properties in vitro and in animal models. Liver vitamin A homeostasis is maintained by cell‐specific enzymatic activities including storage in hepatic stellate cells (HSCs), secretion into circulation fr...
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| Publicado no: | Clin Transl Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8212748/ https://ncbi.nlm.nih.gov/pubmed/33382909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12962 |
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