Altered vitamin A metabolism in human liver slices corresponds to fibrogenesis

ABSTRACT: All‐trans‐retinoic acid (atRA), the active metabolite of vitamin A, has antifibrogenic properties in vitro and in animal models. Liver vitamin A homeostasis is maintained by cell‐specific enzymatic activities including storage in hepatic stellate cells (HSCs), secretion into circulation fr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Transl Sci
Päätekijät: Czuba, Lindsay C., Wu, Xia, Huang, Weize, Hollingshead, Nicole, Roberto, Jessica B., Kenerson, Heidi L., Yeung, Raymond S., Crispe, Ian N., Isoherranen, Nina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2021
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212748/
https://ncbi.nlm.nih.gov/pubmed/33382909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12962
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