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Tyrosine Kinase Inhibitors Reduce Glucose Uptake by Binding to an Exofacial Site on hGLUT‐1: Influence on (18)F‐FDG PET Uptake

Positron emission tomography (PET) using 2‐deoxy‐2‐[(18)F]fluoro‐d‐glucose ([(18)F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growth. Treatment with some tyrosine kinase inhibitors (TKIs)...

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Bibliografische gegevens
Gepubliceerd in:Clin Transl Sci
Hoofdauteurs: Damaraju, Vijaya L., Aminpour, Maral, Kuzma, Michelle, Winter, Philip, Preto, Jordane, Tuszynski, Jack, McEwan, Alexander B.J., Sawyer, Michael B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212708/
https://ncbi.nlm.nih.gov/pubmed/33278334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12943
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