Tyrosine Kinase Inhibitors Reduce Glucose Uptake by Binding to an Exofacial Site on hGLUT‐1: Influence on (18)F‐FDG PET Uptake

Positron emission tomography (PET) using 2‐deoxy‐2‐[(18)F]fluoro‐d‐glucose ([(18)F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growth. Treatment with some tyrosine kinase inhibitors (TKIs)...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Damaraju, Vijaya L., Aminpour, Maral, Kuzma, Michelle, Winter, Philip, Preto, Jordane, Tuszynski, Jack, McEwan, Alexander B.J., Sawyer, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212708/
https://ncbi.nlm.nih.gov/pubmed/33278334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12943
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