Tyrosine Kinase Inhibitors Reduce Glucose Uptake by Binding to an Exofacial Site on hGLUT‐1: Influence on (18)F‐FDG PET Uptake

Positron emission tomography (PET) using 2‐deoxy‐2‐[(18)F]fluoro‐d‐glucose ([(18)F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growth. Treatment with some tyrosine kinase inhibitors (TKIs)...

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Udgivet i:Clin Transl Sci
Main Authors: Damaraju, Vijaya L., Aminpour, Maral, Kuzma, Michelle, Winter, Philip, Preto, Jordane, Tuszynski, Jack, McEwan, Alexander B.J., Sawyer, Michael B.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212708/
https://ncbi.nlm.nih.gov/pubmed/33278334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12943
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