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Tyrosine Kinase Inhibitors Reduce Glucose Uptake by Binding to an Exofacial Site on hGLUT‐1: Influence on (18)F‐FDG PET Uptake

Positron emission tomography (PET) using 2‐deoxy‐2‐[(18)F]fluoro‐d‐glucose ([(18)F]FDG), a marker of energy metabolism and cell proliferation, is routinely used in the clinic to assess patient response to chemotherapy and to monitor tumor growth. Treatment with some tyrosine kinase inhibitors (TKIs)...

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Dettagli Bibliografici
Pubblicato in:Clin Transl Sci
Autori principali: Damaraju, Vijaya L., Aminpour, Maral, Kuzma, Michelle, Winter, Philip, Preto, Jordane, Tuszynski, Jack, McEwan, Alexander B.J., Sawyer, Michael B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212708/
https://ncbi.nlm.nih.gov/pubmed/33278334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12943
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