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Aggregation-induced integrated stress response rejuvenates culture-expanded human mesenchymal stem cells

Protein homeostasis is critical for cellular function, as loss of homeostasis is attributed to aging and the accumulation of unwanted proteins. Human mesenchymal stem cells (MSCs) have shown promising therapeutic potential due to their impressive abilities to secrete inflammatory modulators, angioge...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Bijonowski, Brent M., Fu, Qin, Yuan, Xuegang, Irianto, Jerome, Li, Yan, Grant, Samuel C., Ma, Teng
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212669/
https://ncbi.nlm.nih.gov/pubmed/32579299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27474
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