Mechanistic insights into mitochondrial tRNA(Ala) 3’-end metabolism deficiency

Mitochondrial tRNA 3’-end metabolism is critical for the formation of functional tRNAs. Deficient mitochondrial tRNA 3’-end metabolism is linked to an array of human diseases, including optic neuropathy, but their pathophysiology remains poorly understood. In this report, we investigated the molecul...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Ji, Yanchun, Nie, Zhipeng, Meng, Feilong, Hu, Cuifang, Chen, Hui, Jin, Lihao, Chen, Mengquan, Zhang, Minglian, Zhang, Juanjuan, Liang, Min, Wang, Meng, Guan, Min-Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212662/
https://ncbi.nlm.nih.gov/pubmed/34023389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100816
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