Therapeutic potential of NTRK3 inhibition in desmoplastic small round cell tumor

PURPOSE: Desmoplastic small round cell tumor (DSRCT) is a highly lethal intra-abdominal sarcoma of adolescents and young adults. DSRCT harbors a t(11;22)(p13:q12) that generates the EWSR1-WT1 chimeric transcription factor, the key oncogenic driver of DSRCT. EWSR1-WT1 rewires global gene expression n...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Clin Cancer Res
Main Authors: Ogura, Koichi, Somwar, Romel, Hmeljak, Julija, Magnan, Heather, Benayed, Ryma, Boroujeni, Amir Momeni, Bowman, Anita S., Mattar, Marissa S., Khodos, Inna, de Stanchina, Elisa, Jungbluth, Achim, Asher, Marina, Odintsov, Igor, Hartono, Alifiani B., LaQuaglia, Michael P., Slotkin, Emily, Pratilas, Christine A., Lee, Sean Bong, Spraggon, Lee, Ladanyi, Marc
Formato: Artigo
Idioma:Inglês
Publicado: 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212565/
https://ncbi.nlm.nih.gov/pubmed/33229458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-20-2585
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares