Crosstalk between transforming growth factor β-2 and Autotaxin in trabecular meshwork and different subtypes of glaucoma

BACKGROUND: Elevated transforming growth factor (TGF)-β2 in aqueous humor (AH) has been suggested to contribute to trabecular meshwork (TM) fibrosis and intraocular pressure (IOP) regulation in primary open-angle glaucoma (POAG), but TGF-β2 is downregulated in secondary open-angle glaucoma (SOAG). B...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Igarashi, Nozomi, Honjo, Megumi, Yamagishi, Reiko, Kurano, Makoto, Yatomi, Yutaka, Igarashi, Koji, Kaburaki, Toshikatsu, Aihara, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212476/
https://ncbi.nlm.nih.gov/pubmed/34140021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-021-00745-3
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