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Evaluation of Long-Lasting Potential of Suprachoroidal Axitinib Suspension Via Ocular and Systemic Disposition in Rabbits

PURPOSE: Axitinib, a tyrosine kinase inhibitor, is a potent inhibitor of vascular endothelial growth factor (VEGF) receptors −1, −2 and −3. Suprachoroidal (SC) delivery of axitinib, combined with pan-VEGF inhibition activity of axitinib, has the potential to provide additional benefits compared to t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Transl Vis Sci Technol
Main Authors: Kansara, Viral S., Muya, Leroy W., Ciulla, Thomas A.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212425/
https://ncbi.nlm.nih.gov/pubmed/34128964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.10.7.19
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