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Developmental clock and mechanism of de novo polarization of the mouse embryo
Embryo polarization is critical for mouse development; however, neither the regulatory clock nor the molecular trigger that it activates is known. Here, we show that the embryo polarization clock reflects the onset of zygotic genome activation, and we identify three factors required to trigger polar...
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| Publicado en: | Science |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8210885/ https://ncbi.nlm.nih.gov/pubmed/33303584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abd2703 |
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