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Epigenetic Modification Affecting Expression of Cell Polarity and Cell Fate Genes to Regulate Lineage Specification in the Early Mouse Embryo
Formation of inner and outer cells of the mouse embryo distinguishes pluripotent inner cell mass (ICM) from differentiating trophectoderm (TE). Carm1, which methylates histone H3R17 and R26, directs cells to ICM rather that TE. To understand the mechanism by which this epigenetic modification direct...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2912351/ https://ncbi.nlm.nih.gov/pubmed/20554762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E10-01-0053 |
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