Role of Cdx2 and cell polarity in cell allocation and specification of trophectoderm and inner cell mass in the mouse embryo

Genesis of the trophectoderm and inner cell mass (ICM) lineages occurs in two stages. It is initiated via asymmetric divisions of eight- and 16-cell blastomeres that allocate cells to inner and outer positions, each with different developmental fates. Outside cells become committed to the trophectod...

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Bibliographic Details
Main Authors: Jedrusik, Agnieszka, Parfitt, David-Emlyn, Guo, Guoji, Skamagki, Maria, Grabarek, Joanna B., Johnson, Martin H., Robson, Paul, Zernicka-Goetz, Magdalena
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2008
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2559904/
https://ncbi.nlm.nih.gov/pubmed/18832072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.486108
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