Notopterol Attenuates Estrogen Deficiency-Induced Osteoporosis via Repressing RANKL Signaling and Reactive Oxygen Species

Integrity of the skeleton is sustained through the balanced activities of osteoblasts and osteoclasts in bone remodeling unit. The balance can be disrupted by excessive osteoclasts activation commonly seen in osteoporosis. Notopterol (NOT) is a main component of Notopterygium incisum which exerts a...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Chen, Delong, Wang, Qingqing, Li, Ying, Sun, Ping, Kuek, Vincent, Yuan, Jinbo, Yang, Junzheng, Wen, Longfei, Wang, Haibin, Xu, Jiake, Chen, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210423/
https://ncbi.nlm.nih.gov/pubmed/34149419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.664836
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