The HelQ human DNA repair helicase utilizes a PWI-like domain for DNA loading through interaction with RPA, triggering DNA unwinding by the HelQ helicase core

Genome instability is a characteristic enabling factor for carcinogenesis. HelQ helicase is a component of human DNA maintenance systems that prevent or reverse genome instability arising during DNA replication. Here, we provide details of the molecular mechanisms that underpin HelQ function—its rec...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:NAR Cancer
Hlavní autoři: Jenkins, Tabitha, Northall, Sarah J, Ptchelkine, Denis, Lever, Rebecca, Cubbon, Andrew, Betts, Hannah, Taresco, Vincenzo, Cooper, Christopher D O, McHugh, Peter J, Soultanas, Panos, Bolt, Edward L
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2021
Témata:
DNA Damage Sensing and Repair
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8210318/
https://ncbi.nlm.nih.gov/pubmed/34316696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa043
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky