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Insights into the acquisition of the pks island and production of colibactin in the Escherichia coli population

The pks island codes for the enzymes necessary for synthesis of the genotoxin colibactin, which contributes to the virulence of Escherichia coli strains and is suspected of promoting colorectal cancer. From a collection of 785 human and bovine E. coli isolates, we identified 109 strains carrying a h...

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Détails bibliographiques
Publié dans:Microb Genom
Auteurs principaux: Auvray, Frédéric, Perrat, Alexandre, Arimizu, Yoko, Chagneau, Camille V., Bossuet-Greif, Nadège, Massip, Clémence, Brugère, Hubert, Nougayrède, Jean-Philippe, Hayashi, Tetsuya, Branchu, Priscilla, Ogura, Yoshitoshi, Oswald, Eric
Format: Artigo
Langue:Inglês
Publié: Microbiology Society 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209727/
https://ncbi.nlm.nih.gov/pubmed/33961542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mgen.0.000579
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