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Promotion of Bone Lesions Through the Myeloma Integrin α6-Mediated Osteolytic Signaling

Osteolytic destruction is a hallmark of multiple myeloma and impairs myeloma patients’ quality of life. However, the molecular mechanism underlying the pathogenesis of myeloma-associated bone disease remains unclear. In this study, we demonstrate the role of myeloma cell-expressed integrin α6 in bon...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Liu, Huan, Wang, Zhiming, He, Jin, Li, Zongwei, Gao, Jerry Y., Liu, Rui, Lin, Pei, Yang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209508/
https://ncbi.nlm.nih.gov/pubmed/34150666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.692190
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