ALKBH1-8 and FTO: Potential Therapeutic Targets and Prognostic Biomarkers in Lung Adenocarcinoma Pathogenesis

The AlkB family consists of Fe(II)- and α-ketoglutarate-dependent dioxygenases that can catalyze demethylation on a variety of substrates, such as RNA and DNA, subsequently affecting tumor progression and prognosis. However, their detailed functional roles in lung adenocarcinoma (LUAD) have not been...

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Bibliografiske detaljer
Udgivet i:Front Cell Dev Biol
Main Authors: Wu, Geting, Yan, Yuanliang, Cai, Yuan, Peng, Bi, Li, Juanni, Huang, Jinzhou, Xu, Zhijie, Zhou, Jianhua
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209387/
https://ncbi.nlm.nih.gov/pubmed/34150745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.633927
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