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Current understanding of extrachromosomal circular DNA in cancer pathogenesis and therapeutic resistance

Extrachromosomal circular DNA was recently found to be particularly abundant in multiple human cancer cells, although its frequency varies among different tumor types. Elevated levels of extrachromosomal circular DNA have been considered an effective biomarker of cancer pathogenesis. Multiple report...

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Detalles Bibliográficos
Publicado en:J Hematol Oncol
Main Authors: Yan, Yuanliang, Guo, Guijie, Huang, Jinzhou, Gao, Ming, Zhu, Qian, Zeng, Shuangshuang, Gong, Zhicheng, Xu, Zhijie
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491193/
https://ncbi.nlm.nih.gov/pubmed/32928268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00960-9
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