Current understanding of extrachromosomal circular DNA in cancer pathogenesis and therapeutic resistance

Extrachromosomal circular DNA was recently found to be particularly abundant in multiple human cancer cells, although its frequency varies among different tumor types. Elevated levels of extrachromosomal circular DNA have been considered an effective biomarker of cancer pathogenesis. Multiple report...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Yan, Yuanliang, Guo, Guijie, Huang, Jinzhou, Gao, Ming, Zhu, Qian, Zeng, Shuangshuang, Gong, Zhicheng, Xu, Zhijie
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2020
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7491193/
https://ncbi.nlm.nih.gov/pubmed/32928268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00960-9
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