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miR-199a Overexpression Enhances the Potency of Human Induced-Pluripotent Stem-Cell–Derived Cardiomyocytes for Myocardial Repair

Mammalian cardiomyocytes exit the cell cycle during the perinatal period, and although cardiomyocytes differentiated from human induced-pluripotent stem cells (hiPSC-CMs) are phenotypically immature, their intrinsic cell-cycle activity remains limited. Thus, neither endogenous cardiomyocytes nor the...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Bian, Weihua, Chen, Wangping, Nguyen, Thanh, Zhou, Yang, Zhang, Jianyi
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209326/
https://ncbi.nlm.nih.gov/pubmed/34149424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.673621
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