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Striatal Synapse Degeneration and Dysfunction Are Reversed by Reactivation of Wnt Signaling

Synapse degeneration in the striatum has been associated with the early stages of Parkinson’s and Huntington’s diseases (PD and HD). However, the molecular mechanisms that trigger synaptic dysfunction and loss are not fully understood. Increasing evidence suggests that deficiency in Wnt signaling tr...

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Détails bibliographiques
Publié dans:Front Synaptic Neurosci
Auteurs principaux: Galli, Soledad, Stancheva, Stefka H., Dufor, Tom, Gibb, Alasdair J., Salinas, Patricia C.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209303/
https://ncbi.nlm.nih.gov/pubmed/34149390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2021.670467
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