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Striatal Synapse Degeneration and Dysfunction Are Reversed by Reactivation of Wnt Signaling

Synapse degeneration in the striatum has been associated with the early stages of Parkinson’s and Huntington’s diseases (PD and HD). However, the molecular mechanisms that trigger synaptic dysfunction and loss are not fully understood. Increasing evidence suggests that deficiency in Wnt signaling tr...

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Detalhes bibliográficos
Publicado no:Front Synaptic Neurosci
Main Authors: Galli, Soledad, Stancheva, Stefka H., Dufor, Tom, Gibb, Alasdair J., Salinas, Patricia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209303/
https://ncbi.nlm.nih.gov/pubmed/34149390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnsyn.2021.670467
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